Serial testing using interferon-γ release assays in nursing students in India.
نویسندگان
چکیده
Martin O.C. Ota, Joseph F. Mendy, Simon Donkor, Toyin Togun, Mohammed Daramy, Marie P. Gomez, Novel N. Chegou, Abdou K. Sillah, Olumuyiwa Owolabi, Beate Kampmann, Gerhard Walzl and Jayne S. Sutherland Vaccinology Theme, Medical Research Council Unit, Fajara, the Gambia. DST/NRF Centre of Excellence for Biomedical Tuberculosis Research and MRC Centre for Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Dept of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.
منابع مشابه
Detection of Latent Tuberculosis Infection in Nursing Students by Combined TST and IGRA Serial Testing
Nursing students are Occupationally at risk group for tuberculosis. Tuberculosis can either be as Latent tuberculosis (LTBI) or as active tuberculosis infection (TBI). Lack of awareness and not taking appropriate self defence exposes this group to acquire tuberculosis. it is the prime responsibility of governments and the managements of hospitals must take care of the health care workers. There...
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BACKGROUND Interferon-gamma release assays (IGRA) are used for tuberculosis (TB) screening in healthcare workers (HCWs). However, data on specificity of IGRA in serial testing of HCWs is sparse. Therefore the specificity and the negative predictive value of the IGRA - QuantiFERON-TB Gold In-Tube (QFT) - in German nursing students was investigated. METHODS 194 nursing students at the start of ...
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OBJECTIVES Evidence for the utility of the new Mycobacterium tuberculosis (MTB) specific IFN-γ release assays in diagnosing latent tuberculosis infection (LTBI) is growing. However, data concerning conversion and reversion rates in serial testing of healthcare workers (HCWs) with an interferon-γ release assay are sparse. METHODS Between February 2007 and September 2009, 670 HCWs in the Univer...
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BACKGROUND T cell-based interferon-gamma (IFN-gamma) release assays (IGRAs) are novel tests for latent tuberculosis infection (LTBI). It has been suggested that T cell responses may be correlated with bacterial burden and, therefore, IGRAs may have a role in monitoring treatment response. We investigated IFN-gamma responses to specific TB antigens among Indian health care workers (HCWs) before,...
متن کاملSerial Interferon-gamma Release Assays for the Diagnosis of Latent Tuberculosis Infection in Patients Treated with Immunosuppressive Agents
BACKGROUND We assessed the efficacy of serial interferon-gamma release assays (IGRAs) for the diagnosis of latent tuberculosis infection (LTBI) in patients receiving immunosuppressive agents for treatment of rheumatic diseases in Korea. METHODS Of 276 patients who underwent consecutive screening with one of two IGRAs [QuantiFERON-TB Gold or QuantiFERON-TB Gold In-Tube], 66 patients were evalu...
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ورودعنوان ژورنال:
- The European respiratory journal
دوره 44 1 شماره
صفحات -
تاریخ انتشار 2014